QuickView for CPA6 (gene)

Gene Symbol:

CPA6 Homo sapiens

Full name:

carboxypeptidase A6

Synonyms:

CPAH, ETL5, FEB11, carboxypeptidase A6, carboxypeptidase B

Genomic Location:

Chr 8: 68496962-68821134

Description:

The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptide...

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The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AP1_C ,  TGANTCA_AP1_C ,  AP1_Q6 ,  NFE2_01 ,  AP1_01 ,  BACH2_01 ,  AP1_Q2_01 ,  TGTTTGY_HNF3_Q6 ,  CAGCTG_AP4_Q5 ,  TGASTMAGC_NFE2_01

Cytogenetic Map:

8q13.2

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