QuickView for CRAT (gene)

Gene Symbol:

CRAT Homo sapiens

Full name:

carnitine O-acetyltransferase

Synonyms:

CAT, CAT1, carnitine O-acetyltransferase, carnitine acetylase

Genomic Location:

Chr 9: 130896894-130912904

Description:

This gene encodes carnitine O-acetyltransferase, a member of the carnitine acyltransferase family and a key metabolic pathway enzyme which plays an important role in energy homeostasis and fat metabolism. This enzyme catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acyl-CoA/CoA. It ...

View Full Description

This gene encodes carnitine O-acetyltransferase, a member of the carnitine acyltransferase family and a key metabolic pathway enzyme which plays an important role in energy homeostasis and fat metabolism. This enzyme catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acyl-CoA/CoA. It is found in both the mitochondria and the peroxisome. Alternative splicing results in transcript variants encoding different isoforms that may localize to different subcellular compartments.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CMYB_01 ,  AREB6_02 ,  YGTCCTTGR_UNKNOWN ,  SMAD3_Q6 ,  E2A_Q2 ,  P53_02 ,  CAGGTG_E12_Q6 ,  EVI1_02 ,  MYOD_Q6 ,  GTGCCTT_MIR506 ,  AAAYRNCTG_UNKNOWN ,  KMCATNNWGGA_UNKNOWN ,  TGACAGNY_MEIS1_01 ,  EVI1_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-124a

Cytogenetic Map:

9q34.11

search → result