QuickView for CREB1;jsessionid=E7B5DB9477979439F1C8BE0276B24088 (gene)

Gene Symbol:

CREB1 Homo sapiens

Full name:

cAMP responsive element binding protein 1

Synonyms:

CREB, CREB-1, cyclic AMP-responsive element-binding protein 1, active transcription factor CREB, cAMP-response element-binding protein-1, cyclic adenosine 3',5'-monophosphate response element-binding protein CREB, transactivator protein

Genomic Location:

Chr 2: 208102931-208171818

Description:

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathwa...

View Full Description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CRGAARNNNNCGA_UNKNOWN ,  IRF1_01 ,  GTGTTGA_MIR505 ,  CGCAAAA_MIR450 ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  YTATTTTNR_MEF2_02 ,  NFKAPPAB_01 ,  TTF1_Q6 ,  ACTGTGA_MIR27A_MIR27B ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  NFKAPPAB65_01 ,  WTGAAAT_UNKNOWN ,  HNF4_01 ,  TAATGTG_MIR323 ,  GTGACGY_E4F1_Q6 ,  SP1_Q4_01 ,  TGCGCANK_UNKNOWN ,  TGCCTTA_MIR124A ,  GGGCGGR_SP1_Q6 ,  ACTGCCT_MIR34B ,  E4F1_Q6 ,  AGGTGCA_MIR500 ,  SP1_Q6 ,  RORA1_01 ,  MTF1_Q4 ,  ARGGGTTAA_UNKNOWN ,  MEF2_03 ,  CP2_02 ,  SMAD4_Q6 ,  AGGGCAG_MIR18A ,  CREL_01 ,  RORA2_01 ,  WCAANNNYCAG_UNKNOWN ,  NFKB_Q6_01 ,  AACTTT_UNKNOWN ,  STTTCRNTTT_IRF_Q6 ,  SP1_Q2_01 ,  GGGNNTTTCC_NFKB_Q6_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-34b ,  Predicted Gene Targets for miR-450 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-500 ,  Predicted Gene Targets for miR-505

View More

View Less

Cytogenetic Map:

2q33.3

search → result