QuickView for CRFR2 (gene)

Gene Symbol:

CRHR2 Homo sapiens

Full name:

corticotropin releasing hormone receptor 2

Synonyms:

CRF-RB, CRF2, CRFR2, HM-CRF, corticotropin-releasing factor receptor 2, CRF2 receptor, beta isoform, CRH receptor 2 variant B, CRH-R2

Genomic Location:

Chr 7: 30659388-30688665

Description:

The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in...

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The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GR_Q6

Cytogenetic Map:

7p14.3

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