QuickView for CRHBP;jsessionid=71A56389FA703FE693C9A4EEC1FAD010 (gene)

Gene Symbol:

CRHBP Homo sapiens

Full name:

corticotropin releasing hormone binding protein

Synonyms:

CRF-BP, CRFBP, corticotropin-releasing factor-binding protein, CRF-binding protein, CRH-BP

Genomic Location:

Chr 5: 76284436-76301055

Description:

Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma co...

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Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTANTCA_UNKNOWN ,  TTTGTAG_MIR520D ,  AMEF2_Q6 ,  CREB_Q3 ,  CTTTGTA_MIR524 ,  TATA_C ,  CAGCTG_AP4_Q5 ,  MMEF2_Q6 ,  AACTTT_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-221

miRNA binding sites
(Source: miRecords):

hsa-miR-16 Targeted Genes

Cytogenetic Map:

5q13.3

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