QuickView for CRHR (gene)

Gene Symbol:

CRHR1 Homo sapiens

Full name:

corticotropin releasing hormone receptor 1

Synonyms:

CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRHR, CRHR1L, corticotropin-releasing factor receptor 1, CRH receptor 1, corticotropin-releasing factor type 1 receptor, seven transmembrane helix receptor

Genomic Location:

Chr 17: 41217449-41268973

Description:

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproductio...

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This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGCC_MIR34A_MIR34C_MIR449 ,  CCCAGAG_MIR326 ,  VDR_Q6 ,  GGGAGGRR_MAZ_Q6 ,  GGGCGGR_SP1_Q6 ,  PTF1BETA_Q6 ,  RNGTGGGC_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-326 ,  Predicted Gene Targets for miR-34

Cytogenetic Map:

17q21.31

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