Correlation Engine 2.0
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QuickView for CRLS1 (gene)

Gene Symbol:
CRLS1 Homo sapiens Homo sapiens
Full name:
cardiolipin synthase 1
C20orf155, CLS, CLS1, GCD10, dJ967N21.6, cardiolipin synthase (CMP-forming)
Genomic Location:
Chr 20: 5934879-5966039
This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function.
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 20

GO Molecular Function

phosphotransferase activity, for other substituted phosphate groups | transferase activity, transferring acyl groups other than amino-acyl groups | 2-acylglycerol-3-phosphate O-acyltransferase activity | cardiolipin synthase activity | catalytic activity | lysophosphatidic acid acyltransferase activity | transferase activity, transferring acyl groups | acylglycerol O-acyltransferase activity | CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity | transferase activity, transferring phosphorus-containing groups | transferase activity | lysophospholipid acyltransferase activity | 1-acylglycerol-3-phosphate O-acyltransferase activity | O-acyltransferase activity

GO Biological Process

phosphatidylglycerol acyl-chain remodeling | phosphatidylglycerol metabolic process | response to hormone | phosphatidylglycerol biosynthetic process | response to drug | phospholipid metabolic process | response to organophosphorus | cellular process | cardiolipin biosynthetic process | cellular lipid metabolic process | response to stimulus | cellular biosynthetic process | response to nitrogen compound | phosphorus metabolic process | response to amino acid | lipid metabolic process | response to lipid | organophosphate metabolic process | phospholipid biosynthetic process | cardiolipin metabolic process | biosynthetic process | lipid biosynthetic process | phosphate-containing compound metabolic process | glycerolipid metabolic process | response to organic substance | response to L-phenylalanine derivative | glycerophospholipid biosynthetic process | response to phosphatidylethanolamine | metabolic process | organic substance metabolic process | response to organic cyclic compound | glycerophospholipid metabolic process | response to thyroid hormone | response to organonitrogen compound | response to thyroxine | cellular metabolic process

GO Cellular Component

integral component of membrane | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane