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QuickView for CRP (gene)


Gene Symbol:
CRP Homo sapiens Homo sapiens
Full name:
C-reactive protein
Synonyms:
PTX1, C-reactive protein, C-reactive protein, pentraxin-related, pentraxin 1
Genomic Location:
Chr 1: 157948703-157951003
Description:
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1q23.2





GO Molecular Function

opsonin binding | low-density lipoprotein particle receptor binding | cation binding | neurotransmitter binding | protein-containing complex binding | lipoprotein particle receptor binding | complement binding | signaling receptor binding | choline binding | lipoprotein particle binding | complement component C1q binding | identical protein binding | ion binding | low-density lipoprotein particle binding | protein binding | virion binding | calcium ion binding | metal ion binding

GO Biological Process

positive regulation of immune response | adaptive immune response | regulation of blood vessel diameter | regulation of localization | complement activation | defense response to other organism | establishment of localization | regulation of immune system process | negative regulation of cellular process | opsonization | defense response | localization | positive regulation of reactive oxygen species metabolic process | regulation of cell differentiation | regulation of immune response | regulation of cellular process | regulation of metabolic process | regulation of peptide secretion | response to stimulus | regulation of interleukin-8 secretion | regulation of macrophage derived foam cell differentiation | positive regulation of immune system process | regulation of blood vessel size | response to stress | positive regulation of superoxide anion generation | regulation of protein transport | blood circulation | regulation of peptide transport | regulation of lipid storage | negative regulation of blood vessel diameter | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | regulation of superoxide metabolic process | response to external biotic stimulus | nitrogen compound metabolic process | leukocyte mediated immunity | regulation of gene expression | positive regulation of cellular metabolic process | negative regulation of lipid storage | vesicle-mediated transport | acute-phase response | protein activation cascade | response to bacterium | regulation of cellular metabolic process | humoral immune response | inflammatory response | defense response to bacterium | regulation of tube size | regulation of cytokine secretion | activation of immune response | protein metabolic process | regulation of establishment of protein localization | import into cell | complement activation, classical pathway | metabolic process | regulation of tube diameter | endocytosis | regulation of secretion | immune response | organic substance metabolic process | regulation of protein secretion | negative regulation of macrophage derived foam cell differentiation | defense response to Gram-positive bacterium | humoral immune response mediated by circulating immunoglobulin | regulation of cytokine production | response to biotic stimulus | regulation of developmental process | B cell mediated immunity | regulation of transport | regulation of reactive oxygen species metabolic process | regulation of superoxide anion generation | innate immune response | positive regulation of metabolic process | acute inflammatory response | immunoglobulin mediated immune response | immune system process | regulation of protein localization | phagocytosis | negative regulation of cell differentiation | response to other organism | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

extracellular region | extracellular space