QuickView for CS-5 (gene)

Gene Symbol:

CSHL1 Homo sapiens

Full name:

chorionic somatomammotropin hormone like 1

Synonyms:

CS-5, CSHP1, CSL, GHB4, hCS-L, chorionic somatomammotropin hormone-like 1, chorionic somatomammotropin CS-5, growth hormone B4, growth hormone cluster

Genomic Location:

Chr 17: 59340697-59342350

Description:

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to h...

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The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified.

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External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGGAGGRR_MAZ_Q6 ,  TATAAA_TATA_01 ,  POU1F1_Q6 ,  TATA_01

miRNA binding sites
(Source: miRecords):

hsa-miR-16 Targeted Genes

Cytogenetic Map:

17q23.3

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