QuickView for CSF-1 (gene)

Gene Symbol:

CSF1 Homo sapiens

Full name:

colony stimulating factor 1

Synonyms:

CSF-1, MCSF, macrophage colony-stimulating factor 1, colony stimulating factor 1 (macrophage), lanimostim, macrophage colony stimulating factor 1

Genomic Location:

Chr 1: 110254980-110273878

Description:

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of ...

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The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGTG_MIR128A_MIR128B ,  PU1_Q6 ,  TTGCACT_MIR130A_MIR301_MIR130B ,  ACTGTGA_MIR27A_MIR27B ,  TGCACTG_MIR148A_MIR152_MIR148B ,  AGCTCCT_MIR28 ,  GTGCCAA_MIR96 ,  TCCAGAT_MIR5165P ,  CCTGCTG_MIR214 ,  RGAGGAARY_PU1_Q6 ,  ELF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-214 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-28 ,  Predicted Gene Targets for miR-96

miRNA binding sites
(Source: miRecords):

hsa-miR-130a Targeted Genes

Cytogenetic Map:

1p13.3

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