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QuickView for CSF2RX (gene)


Gene Symbol:
CSF2RA Homo sapiens Homo sapiens
Full name:
colony stimulating factor 2 receptor alpha subunit
Synonyms:
CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4, alphaGMR, granulocyte-macrophage colony-stimulating factor receptor subunit alpha, CD116 antigen, GM-CSF receptor alpha subunit, GMCSFR-alpha, GMR-alpha, alpha-GM-CSF receptor, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), granulocyte-macrophage colony-stimulating factor receptor alpha chain
Genomic Location:
Chr X: 1347701-1388827
Description:
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of t...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr X
Xp22.33 and Yp11.2





GO Molecular Function

cytokine binding | guanyl-nucleotide exchange factor activity | GTPase binding | transmembrane signaling receptor activity | enzyme binding | Ras GTPase binding | molecular function regulator | catalytic activity | signaling receptor activity | cytokine receptor activity | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | Ras guanyl-nucleotide exchange factor activity | protein kinase activity | transferase activity | small GTPase binding | kinase activity

GO Biological Process

guanyl-nucleotide exchange factor activity | response to cytokine | intracellular signal transduction | peptidyl-amino acid modification | peptidyl-tyrosine phosphorylation | cellular process | regulation of cellular process | MAPK cascade | response to stimulus | signal transduction by protein phosphorylation | protein modification process | macromolecule modification | molecular function regulator | nitrogen compound metabolic process | phosphorus metabolic process | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cytokine receptor activity | cell communication | protein tyrosine kinase activity | protein metabolic process | response to organic substance | cell surface receptor signaling pathway | metabolic process | Ras guanyl-nucleotide exchange factor activity | protein kinase activity | organic substance metabolic process | signaling | cellular protein metabolic process | kinase activity | cellular protein modification process | cellular metabolic process | cellular response to organic substance | signal transduction | macromolecule metabolic process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | external side of plasma membrane | receptor complex | protein-containing complex | plasma membrane | integral component of plasma membrane | extracellular region | cell periphery | cell surface | intracellular | membrane | intrinsic component of plasma membrane