QuickView for CSPG1 (gene)

Gene Symbol:

ACAN Homo sapiens

Full name:

aggrecan

Synonyms:

AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK, SSOAOD, aggrecan core protein, cartilage-specific proteoglycan core protein, chondroitin sulfate proteoglycan core protein 1, large aggregating proteoglycan

Genomic Location:

Chr 15: 87147678-87219589

Description:

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that enco...

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This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTGCWCAAY_CEBPB_02 ,  CACGTG_MYC_Q2 ,  CEBP_Q2_01 ,  MEIS1BHOXA9_01 ,  NFKAPPAB_01 ,  NFKAPPAB65_01 ,  GGGAGGRR_MAZ_Q6 ,  CEBPB_01 ,  DBP_Q6 ,  AREB6_01 ,  CEBPB_02 ,  CTGAGCC_MIR24 ,  CREL_01 ,  CACBINDINGPROTEIN_Q6 ,  AACTTT_UNKNOWN ,  PAX4_03 ,  NFKB_C ,  GGGTGGRR_PAX4_03

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Cytogenetic Map:

15q26.1

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