QuickView for CTSB;jsessionid=770780A795AED8DF99572C401482E993;jsessionid=516CC89960472D5F18CD0FE4582DD375 (gene)

Gene Symbol:

Ctsb Mus musculus

Full name:

cathepsin B

Synonyms:

CB, cathepsin B, cathepsin B1

Genomic Location:

Chr 14: 63741302-63764758

Description:

This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and e...

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This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Bos taurus ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ATTCTTT_MIR186

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-186

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