QuickView for CTSH;jsessionid=91BC1990B7EBE0741E0D812445D99AB6 (gene)

Gene Symbol:

CTSH Homo sapiens

Full name:

cathepsin H

Synonyms:

ACC-4, ACC-5, ACC4, ACC5, CPSB, pro-cathepsin H, N-benzoylarginine-beta-naphthylamide hydrolase, aleurain, cathepsin B3, cathepsin BA

Genomic Location:

Chr 15: 77001147-77024475

Description:

The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase ...

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The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes ,  Gallus gallus

External Links:

Entrez Gene

Cytogenetic Map:

15q25.1

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