Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for CTSX (gene)


Gene Symbol:
CTSZ Homo sapiens Homo sapiens
Full name:
cathepsin Z
Synonyms:
CTSX, cathepsin Z, carboxypeptidase LB, cathepsin B2, cathepsin IV, cathepsin P, cathepsin X, cathepsin Y, cathepsin Z1, cysteine-type carboxypeptidase, lysosomal carboxypeptidase B, preprocathepsin P
Genomic Location:
Chr 20: 57003635-57015697
Description:
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other memb...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Bos taurus Gallus gallus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 20
20q13.32


Transcripts Names
NM_001336
Protein Names
Q9UQV5
Q9UBR2
Q9UQV6
O75331
B2RC40



GO Molecular Function

carboxypeptidase activity | hydrolase activity | cysteine-type peptidase activity | catalytic activity | exopeptidase activity | cysteine-type endopeptidase activity | protein binding | endopeptidase activity | peptidase activity

GO Biological Process

exocytosis | regulation of systemic arterial blood pressure by hormone | regulation of neurogenesis | neutrophil activation | positive regulation of apoptotic process | proteolysis | regulation of cell development | morphogenesis of an epithelium | regulation of programmed cell death | establishment of localization | negative regulation of cellular process | protein processing | cell differentiation | respiratory tube development | nervous system development | neurogenesis | generation of neurons | membrane organization | intracellular transport | negative regulation of proteolysis | regulation of neuron death | cellular process | secretion | organic substance catabolic process | leukocyte degranulation | establishment of organelle localization | localization | epithelial tube morphogenesis | proteolysis involved in cellular protein catabolic process | regulation of proteolysis | regulation of neuron projection development | carboxypeptidase activity | establishment of localization in cell | negative regulation of cellular metabolic process | tissue development | regulation of binding | vesicle targeting, to, from or within Golgi | regulation of cell differentiation | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | catabolic process | organelle localization | epithelium development | cellular component organization | epithelial tube branching involved in lung morphogenesis | regulation of systemic arterial blood pressure mediated by a chemical signal | response to stimulus | neutrophil degranulation | respiratory system development | regulation of plasminogen activation | COPII-coated vesicle budding | leukocyte activation involved in immune response | regulation of cell proliferation | negative regulation of neuron projection development | tube morphogenesis | cellular protein catabolic process | cellular localization | secretion by cell | cellular nitrogen compound metabolic process | blood circulation | negative regulation of metabolic process | regulation of angiotensin levels in blood | cellular component assembly | regulation of protein processing | vesicle targeting | cysteine-type peptidase activity | system development | nitrogen compound metabolic process | multicellular organism development | leukocyte mediated immunity | regulation of hormone levels | regulation of neuron differentiation | regulation of gene expression | vesicle coating | protein catabolic process | regulation of blood pressure | regulation of systemic arterial blood pressure by renin-angiotensin | regulation of systemic arterial blood pressure | exopeptidase activity | animal organ morphogenesis | regulation of nitrogen compound metabolic process | cellular amide metabolic process | vesicle-mediated transport | negative regulation of binding | Golgi vesicle budding | establishment of vesicle localization | regulation of cellular protein metabolic process | regulated exocytosis | positive regulation of neuron death | protein maturation | endocrine process | negative regulation of protein binding | regulation of cellular metabolic process | regulation of neuron apoptotic process | cell activation involved in immune response | negative regulation of protein processing | myeloid cell activation involved in immune response | regulation of protein metabolic process | neutrophil activation involved in immune response | positive regulation of cell proliferation | peptide metabolic process | cysteine-type endopeptidase activity | Golgi vesicle transport | negative regulation of plasminogen activation | protein-containing complex assembly | protein metabolic process | negative regulation of cell projection organization | tissue morphogenesis | branching morphogenesis of an epithelial tube | cellular macromolecule catabolic process | positive regulation of neuron apoptotic process | anatomical structure development | regulation of neural precursor cell proliferation | metabolic process | positive regulation of cell death | immune response | organic substance metabolic process | negative regulation of gene expression | animal organ development | negative regulation of neuron differentiation | negative regulation of cellular protein metabolic process | gene expression | positive regulation of programmed cell death | angiotensin maturation | regulation of systemic arterial blood pressure by circulatory renin-angiotensin | peptide hormone processing | vesicle organization | vesicle budding from membrane | cell activation | lung development | morphogenesis of a branching epithelium | negative regulation of protein metabolic process | organonitrogen compound catabolic process | negative regulation of molecular function | ER to Golgi vesicle-mediated transport | regulation of protein binding | endopeptidase activity | cellular protein metabolic process | hormone metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | regulation of nervous system development | regulation of developmental process | positive regulation of neural precursor cell proliferation | developmental process | organelle organization | COPII vesicle coating | tube development | neutrophil mediated immunity | lung morphogenesis | vesicle localization | regulation of cell projection organization | immune system process | cellular metabolic process | peptidase activity | regulation of cell death | negative regulation of cell development | negative regulation of cell differentiation | regulation of cellular component organization | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

secretory granule | endoplasmic reticulum-Golgi intermediate compartment | intracellular membrane-bounded organelle | neuron projection | organelle membrane | cytoplasmic vesicle | cell | COPII-coated ER to Golgi transport vesicle | distal axon | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | endoplasmic reticulum | ficolin-1-rich granule lumen | Golgi apparatus | endoplasmic reticulum-Golgi intermediate compartment membrane | cell projection | secretory vesicle | endomembrane system | plasma membrane | Golgi-associated vesicle | vacuole | vesicle | endoplasmic reticulum lumen | extracellular exosome | cytoplasmic region | specific granule | site of polarized growth | lytic vacuole | Golgi membrane | cell cortex region | extracellular region | cell cortex | membrane-bounded organelle | extracellular vesicle | specific granule lumen | organelle | lysosome | extracellular space | cell periphery | axon | membrane-enclosed lumen | growth cone | secretory granule lumen | intracellular vesicle | cell surface | intracellular | membrane | vesicle lumen | coated vesicle