QuickView for CUL2 (gene)
- Gene Symbol:
- CUL2
Homo sapiens - Full name:
- cullin 2
- Synonyms:
- cullin-2, CUL-2, testis secretory sperm-binding protein Li 238E
- Genomic Location:
- Chr 10: 35338804-35419300
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
10p11.21
GO Molecular Function
enzyme binding | protein-containing complex binding | catalytic activity | ubiquitin-like protein ligase binding | ubiquitin-like protein transferase activity | ubiquitin protein ligase activity | protein binding | ubiquitin protein ligase binding | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity
GO Biological Process
cellular response to decreased oxygen levels | intracellular signal transduction | proteolysis | negative regulation of cellular process | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | response to hypoxia | regulation of cell cycle | interspecies interaction between organisms | intrinsic apoptotic signaling pathway | regulation of cellular process | regulation of metabolic process | catabolic process | response to stimulus | cellular response to hypoxia | response to stress | regulation of cell proliferation | programmed cell death | cellular protein catabolic process | cell cycle G1/S phase transition | protein modification process | macromolecule modification | regulation of nucleic acid-templated transcription | apoptotic process | response to oxygen levels | nitrogen compound metabolic process | regulation of gene expression | cellular response to stress | cell cycle | protein catabolic process | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | regulation of transcription by RNA polymerase II | ubiquitin protein ligase activity | mitotic cell cycle phase transition | cell communication | regulation of cellular metabolic process | G1/S transition of mitotic cell cycle | regulation of RNA metabolic process | viral process | apoptotic signaling pathway | protein metabolic process | protein ubiquitination | cell cycle arrest | cellular macromolecule catabolic process | mitotic cell cycle | metabolic process | regulation of DNA-templated transcription in response to stress | ubiquitin-protein transferase activity | regulation of RNA biosynthetic process | organic substance metabolic process | cell death | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | negative regulation of cell cycle | organonitrogen compound catabolic process | signaling | regulation of transcription, DNA-templated | cellular protein metabolic process | regulation of transcription from RNA polymerase II promoter in response to stress | regulation of transcription from RNA polymerase II promoter in response to hypoxia | cellular protein modification process | negative regulation of cell proliferation | cell cycle phase transition | cellular metabolic process | modification-dependent protein catabolic process | signal transduction | post-translational protein modification | macromolecule metabolic process
GO Cellular Component
Cul2-RING ubiquitin ligase complex | intracellular membrane-bounded organelle | catalytic complex | VCB complex | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | ubiquitin ligase complex | protein-containing complex | nucleoplasm | transferase complex | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular | cytoplasmic ubiquitin ligase complex
