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QuickView for CUX1 (gene)


Gene Symbol:
CUX1 Homo sapiens Homo sapiens
Full name:
cut like homeobox 1
Synonyms:
CASP, CDP, CDP/Cut, CDP1, COY1, CUTL1, CUX, Clox, Cux/CDP, GOLIM6, Nbla10317, p100, p110, p200, p75, protein CASP, CCAAT displacement protein, cut homolog, golgi integral membrane protein 6, homeobox protein cux-1, putative protein product of Nbla10317
Genomic Location:
Chr 7: 101246012-101713970
Description:
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 7
7q22.1





GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | nucleic acid binding | catalytic activity | protein binding, bridging | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | molecular adaptor activity | transcription regulatory region sequence-specific DNA binding | protein tyrosine kinase activity | protein binding | double-stranded DNA binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | RNA polymerase II regulatory region sequence-specific DNA binding | protein kinase activity | transferase activity | kinase activity | heterocyclic compound binding

GO Biological Process

RNA metabolic process | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | regulation of cell development | peptidyl-amino acid modification | establishment of localization | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | nervous system development | neurogenesis | peptidyl-tyrosine phosphorylation | generation of neurons | cellular process | intra-Golgi vesicle-mediated transport | localization | negative regulation of nucleic acid-templated transcription | regulation of neuron projection development | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | positive regulation of dendrite morphogenesis | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | protein modification process | cellular biosynthetic process | macromolecule modification | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | positive regulation of neuron projection development | multicellular organism development | phosphorus metabolic process | regulation of neuron differentiation | regulation of gene expression | regulation of nitrogen compound metabolic process | positive regulation of cell projection organization | vesicle-mediated transport | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | biosynthetic process | aromatic compound biosynthetic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | Golgi vesicle transport | regulation of RNA metabolic process | positive regulation of dendrite development | protein tyrosine kinase activity | regulation of cell morphogenesis involved in differentiation | protein metabolic process | retrograde transport, vesicle recycling within Golgi | anatomical structure development | regulation of dendrite morphogenesis | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription, DNA-templated | regulation of dendrite development | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of nervous system development | regulation of developmental process | kinase activity | developmental process | cellular protein modification process | negative regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of neuron differentiation | regulation of cell projection organization | cellular metabolic process | positive regulation of cell morphogenesis involved in differentiation | regulation of cellular component organization | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | nuclear lumen | cytoplasm | intracellular organelle | Golgi apparatus | endomembrane system | nucleoplasm | Golgi membrane | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular | membrane