QuickView for CXCL5 (gene)

Gene Symbol:

CXCL5 Homo sapiens

Full name:

C-X-C motif chemokine ligand 5

Synonyms:

ENA-78, SCYB5, C-X-C motif chemokine 5, chemokine (C-X-C motif) ligand 5, epithelial-derived neutrophil-activating protein 78, neutrophil-activating peptide ENA-78, neutrophil-activating protein 78, small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78)

Genomic Location:

Chr 4: 75080223-75083280

Description:

This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenes...

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This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion.

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Orthologs:

Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  TGANTCA_AP1_C ,  GGGACCA_MIR133A_MIR133B ,  NFKAPPAB_01 ,  GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  GCAAAAA_MIR129 ,  AATGTGA_MIR23A_MIR23B ,  GATA4_Q3 ,  GATA1_05 ,  IK3_01 ,  SRF_Q5_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-208 ,  Predicted Gene Targets for miR-21 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-450 ,  Predicted Gene Targets for miR-499

Cytogenetic Map:

4q13.3

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