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QuickView for CXCL9 (gene)


Gene Symbol:
CXCL9 Homo sapiens Homo sapiens
Full name:
C-X-C motif chemokine ligand 9
Synonyms:
CMK, Humig, MIG, SCYB9, crg-10, C-X-C motif chemokine 9, chemokine (C-X-C motif) ligand 9, gamma-interferon-induced monokine, monokine induced by gamma interferon, monokine induced by interferon-gamma, small-inducible cytokine B9
Genomic Location:
Chr 4: 77141647-77147665
Description:
This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 4
4q21.1


Transcripts Names
NM_002416
Protein Names
Q503B4
Q07325



GO Molecular Function

chemokine activity | signaling receptor binding | cytokine receptor binding | CXCR chemokine receptor binding | molecular function regulator | CXCR3 chemokine receptor binding | chemokine receptor binding | protein binding | receptor regulator activity | G-protein coupled receptor binding | receptor ligand activity | cytokine activity

GO Biological Process

positive regulation of release of sequestered calcium ion into cytosol | positive regulation of striated muscle cell differentiation | regulation of myoblast fusion | response to virus | response to cytokine | positive regulation of cellular component organization | cell motility | response to lipopolysaccharide | regulation of cellular localization | intracellular signal transduction | regulation of localization | defense response to other organism | positive regulation of developmental process | chemokine-mediated signaling pathway | defense response | cellular chemical homeostasis | cellular process | localization | cellular homeostasis | regulation of syncytium formation by plasma membrane fusion | chemokine activity | granulocyte chemotaxis | regulation of cell differentiation | positive regulation of muscle cell differentiation | regulation of myotube differentiation | regulation of cellular process | cellular response to lipid | regulation of cytosolic calcium ion concentration | cellular response to molecule of bacterial origin | calcium ion homeostasis | response to stimulus | neutrophil chemotaxis | response to stress | positive regulation of cation transmembrane transport | regulation of cell proliferation | response to molecule of bacterial origin | positive regulation of myoblast differentiation | G-protein coupled receptor signaling pathway | cell-cell signaling | cell chemotaxis | molecular function regulator | metal ion homeostasis | leukocyte migration | locomotion | regulation of calcium ion transport into cytosol | response to external biotic stimulus | regulation of signal transduction | positive regulation of calcium ion transmembrane transport | cell migration | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | response to lipid | defense response to virus | cellular ion homeostasis | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | positive regulation of syncytium formation by plasma membrane fusion | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | positive regulation of cell differentiation | second-messenger-mediated signaling | regulation of release of sequestered calcium ion into cytosol | cellular response to cytokine stimulus | regulation of calcium ion transmembrane transport | cation homeostasis | response to bacterium | cellular cation homeostasis | cell communication | antimicrobial humoral immune response mediated by antimicrobial peptide | humoral immune response | inflammatory response | cyclic-nucleotide-mediated signaling | positive regulation of signal transduction | regulation of cAMP-mediated signaling | leukocyte chemotaxis | cellular calcium ion homeostasis | homeostatic process | positive regulation of transport | regulation of signaling receptor activity | antimicrobial humoral response | receptor regulator activity | response to organic substance | cAMP-mediated signaling | regulation of intracellular signal transduction | cell surface receptor signaling pathway | regulation of myoblast differentiation | positive regulation of myoblast fusion | chemical homeostasis | receptor ligand activity | immune response | cytokine activity | regulation of sequestering of calcium ion | positive regulation of ion transport | positive regulation of cAMP-mediated signaling | ion homeostasis | regulation of striated muscle cell differentiation | regulation of ion transmembrane transport | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | positive regulation of calcium ion transport into cytosol | response to biotic stimulus | regulation of developmental process | regulation of ion transport | regulation of muscle cell differentiation | regulation of calcium ion transport | regulation of transport | cellular defense response | cellular metal ion homeostasis | immune system process | cellular response to organic substance | neutrophil migration | chemotaxis | divalent inorganic cation homeostasis | regulation of cellular component organization | positive regulation of calcium ion transport | response to other organism | positive regulation of signaling | positive regulation of myotube differentiation | signal transduction | regulation of signaling | cellular response to lipopolysaccharide

GO Cellular Component

cell | external side of plasma membrane | plasma membrane | extracellular region | extracellular space | cell periphery | cell surface | intracellular | membrane