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QuickView for CXCR5 (gene)


Gene Symbol:
CXCR5 Homo sapiens Homo sapiens
Full name:
C-X-C motif chemokine receptor 5
Synonyms:
BLR1, CD185, MDR15, C-X-C chemokine receptor type 5, Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5), Burkitt lymphoma receptor 1, GTP-binding protein, CXC-R5, CXCR-5, MDR-15, chemokine (C-X-C motif) receptor 5, monocyte-derived receptor 15
Genomic Location:
Chr 11: 118259777-118272181
Description:
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript varia...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11q23.3


Transcripts Names
NM_001716
NM_032966
Protein Names
A0N0R2
A8K647
Q14811
Q2YD84
P32302



GO Molecular Function

cytokine binding | transmembrane signaling receptor activity | G-protein coupled receptor activity | chemokine binding | signaling receptor activity | G-protein coupled chemoattractant receptor activity | cytokine receptor activity | protein binding | C-C chemokine receptor activity | peptide receptor activity | chemokine receptor activity | G-protein coupled peptide receptor activity | C-C chemokine binding | C-X-C chemokine receptor activity

GO Biological Process

regulation of cell cycle process | response to cytokine | cell motility | intracellular signal transduction | chemokine-mediated signaling pathway | cellular chemical homeostasis | cellular process | localization | cellular homeostasis | immune system development | regulation of cell cycle | positive regulation of cell division | positive regulation of cytokinesis | regulation of cellular process | leukocyte activation | regulation of cytosolic calcium ion concentration | calcium ion homeostasis | regulation of cell division | G-protein coupled receptor activity | response to stimulus | G-protein coupled receptor signaling pathway | cell chemotaxis | metal ion homeostasis | leukocyte migration | locomotion | system development | multicellular organism development | cell migration | positive regulation of cell cycle | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | cytokine-mediated signaling pathway | G-protein coupled chemoattractant receptor activity | second-messenger-mediated signaling | cellular response to cytokine stimulus | B cell activation | cation homeostasis | cytokine receptor activity | cellular cation homeostasis | cell communication | regulation of cytokinesis | leukocyte chemotaxis | cellular calcium ion homeostasis | homeostatic process | lymphocyte activation | calcium-mediated signaling | lymph node development | response to organic substance | anatomical structure development | cell surface receptor signaling pathway | chemical homeostasis | immune response | animal organ development | ion homeostasis | cell activation | C-C chemokine receptor activity | chemokine receptor activity | signaling | G-protein coupled peptide receptor activity | developmental process | positive regulation of cell cycle process | C-X-C chemokine receptor activity | cellular metal ion homeostasis | immune system process | hematopoietic or lymphoid organ development | cellular response to organic substance | chemotaxis | divalent inorganic cation homeostasis | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | external side of plasma membrane | plasma membrane | integral component of plasma membrane | cell periphery | cell surface | membrane | intrinsic component of plasma membrane