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QuickView for CYB5A (gene)


Gene Symbol:
CYB5A Homo sapiens Homo sapiens
Full name:
cytochrome b5 type A
Synonyms:
CYB5, MCB5, cytochrome b5, cytochrome b5 type A (microsomal), type 1 cyt-b5
Genomic Location:
Chr 18: 70071507-70110201
Description:
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Danio rerio Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 18
18q22.3





GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | cofactor binding | cytochrome-c oxidase activity | proton transmembrane transporter activity | cation binding | enzyme binding | transmembrane transporter activity | aldo-keto reductase (NADP) activity | catalytic activity | electron transfer activity | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | heme-copper terminal oxidase activity | tetrapyrrole binding | protein binding | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | heme binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

oxidoreductase activity, acting on CH-OH group of donors | cytochrome-c oxidase activity | establishment of localization | proton transmembrane transporter activity | response to metal ion | generation of precursor metabolites and energy | cellular process | proton transmembrane transport | localization | response to inorganic substance | transmembrane transporter activity | response to stimulus | aldo-keto reductase (NADP) activity | electron transport chain | cofactor metabolic process | ion transmembrane transport | electron transfer activity | cation transmembrane transporter activity | monovalent inorganic cation transport | monosaccharide metabolic process | small molecule metabolic process | ion transmembrane transporter activity | response to cadmium ion | carbohydrate metabolic process | L-ascorbic acid metabolic process | heme-copper terminal oxidase activity | carboxylic acid metabolic process | cation transmembrane transport | vitamin metabolic process | metabolic process | oxidation-reduction process | organic substance metabolic process | inorganic cation transmembrane transport | transmembrane transport | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | organic acid metabolic process | cation transport | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | ion transport | cellular metabolic process | oxidoreductase activity

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | organelle outer membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | mitochondrion | membrane-bounded organelle | organelle | mitochondrial outer membrane | mitochondrial envelope | outer membrane | mitochondrial membrane | cytosol | intracellular | membrane