QuickView for CYCT1 (gene)
- Gene Symbol:
- CCNT1
Homo sapiens - Full name:
- cyclin T1
- Synonyms:
- CCNT, CYCT1, HIVE1, cyclin-T1, CDK9-associated C-type protein, MLLT10/CCNT1 fusion, cyclin C-related protein, human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1
- Genomic Location:
- Chr 12: 47373019-47397048
- Description:
-
This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyc...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Bos taurus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
E2F4DP1_01 , E2F_Q6 , GTGACGY_E4F1_Q6 , E2F1_Q6_01 , E2F_Q4 , E2F1DP2_01 , E2F1DP1_01 , ELK1_01 , E2F1DP1RB_01 , SCGGAAGY_ELK1_02
- Cytogenetic Map:
-
12q13.11-q13.12
GO Molecular Function
kinase binding | protein kinase regulator activity | transcription regulatory region DNA binding | 7SK snRNA binding | RNA polymerase binding | kinase regulator activity | protein kinase binding | enzyme binding | nucleic acid binding | protein serine/threonine kinase activity | molecular function regulator | catalytic activity | chromatin binding | DNA binding | organic cyclic compound binding | protein binding | transcription factor binding | snRNA binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | enzyme regulator activity | kinase activity | heterocyclic compound binding | cyclin-dependent protein serine/threonine kinase regulator activity | RNA binding
GO Biological Process
positive regulation of cyclin-dependent protein serine/threonine kinase activity | RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | snRNA metabolic process | protein kinase regulator activity | negative regulation of cellular process | regulation of mRNA polyadenylation | positive regulation of phosphate metabolic process | interaction with symbiont | regulation of mRNA processing | positive regulation of cellular biosynthetic process | cellular process | kinase regulator activity | positive regulation of protein kinase activity | regulation of phosphorylation of RNA polymerase II C-terminal domain | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | snRNA transcription | negative regulation of cellular metabolic process | interspecies interaction between organisms | regulation of cellular process | regulation of metabolic process | positive regulation by host of viral transcription | positive regulation of cyclin-dependent protein kinase activity | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | positive regulation of protein metabolic process | cellular nitrogen compound biosynthetic process | snRNA transcription by RNA polymerase II | protein serine/threonine kinase activity | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | protein modification process | cellular biosynthetic process | macromolecule modification | negative regulation of mRNA polyadenylation | molecular function regulator | regulation of nucleic acid-templated transcription | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | positive regulation of viral process | phosphorus metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | ncRNA transcription | positive regulation of cell cycle | regulation of gene expression | cell cycle | modification of morphology or physiology of other organism | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of mRNA 3'-end processing | positive regulation of phosphorylation of RNA polymerase II C-terminal domain | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | cell division | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | phosphorylation | negative regulation of mRNA processing | negative regulation of mRNA 3'-end processing | transcription elongation from RNA polymerase II promoter | protein phosphorylation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | viral process | regulation of viral process | positive regulation of molecular function | protein metabolic process | positive regulation of protein modification process | regulation of kinase activity | positive regulation of viral transcription | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | negative regulation of gene expression | gene expression | positive regulation of kinase activity | regulation of phosphate metabolic process | transcription, DNA-templated | modulation by host of viral transcription | regulation of transcription, DNA-templated | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | cellular macromolecule biosynthetic process | kinase activity | cellular protein modification process | positive regulation of transcription, DNA-templated | ncRNA metabolic process | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | regulation of viral transcription | positive regulation of metabolic process | cellular metabolic process | positive regulation of gene expression | cyclin-dependent protein serine/threonine kinase regulator activity | macromolecule metabolic process | DNA-templated transcription, elongation | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | transcription elongation factor complex | protein kinase complex | cell | nuclear lumen | cyclin/CDK positive transcription elongation factor complex | nucleolus | intracellular organelle | carboxy-terminal domain protein kinase complex | protein-containing complex | nucleoplasm | nuclear cyclin-dependent protein kinase holoenzyme complex | transferase complex | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cyclin-dependent protein kinase holoenzyme complex | intracellular
