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QuickView for CYP11A1 (gene)

Gene Symbol:
CYP11A1 Homo sapiens Homo sapiens
Full name:
cytochrome P450 family 11 subfamily A member 1
CYP11A, CYPXIA1, P450SCC, cholesterol side-chain cleavage enzyme, mitochondrial, cholesterol 20-22 desmolase, cholesterol monooxygenase (side-chain cleaving), cytochrome P450 11A1, cytochrome P450 family 11 subfamily A polypeptide 1, cytochrome P450(scc), cytochrome P450, subfamily XIA (cholesterol side chain cleavage), steroid 20-22-lyase
Genomic Location:
Chr 15: 72417156-72447134
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnen...
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 15

GO Molecular Function

cofactor binding | cation binding | steroid hydroxylase activity | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | tetrapyrrole binding | protein binding | cholesterol monooxygenase (side-chain-cleaving) activity | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

response to hormone | sterol metabolic process | cellular process | response to peptide hormone | steroid hydroxylase activity | organic cyclic compound metabolic process | cellular response to organonitrogen compound | steroid biosynthetic process | response to stimulus | alcohol metabolic process | response to peptide | cellular biosynthetic process | organic hydroxy compound metabolic process | response to nitrogen compound | cellular response to hormone stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | cellular response to peptide hormone stimulus | hormone biosynthetic process | lipid metabolic process | regulation of hormone levels | cellular response to peptide | small molecule metabolic process | biosynthetic process | lipid biosynthetic process | response to organic substance | vitamin metabolic process | metabolic process | cholesterol metabolic process | oxidation-reduction process | cholesterol monooxygenase (side-chain-cleaving) activity | organic substance metabolic process | C21-steroid hormone metabolic process | steroid metabolic process | glucocorticoid metabolic process | hormone metabolic process | C21-steroid hormone biosynthetic process | glucocorticoid biosynthetic process | response to organonitrogen compound | cellular metabolic process | cellular response to organic substance | oxidoreductase activity | vitamin D metabolic process

GO Cellular Component

mitochondrial matrix | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | membrane-enclosed lumen | mitochondrial membrane | intracellular | membrane