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QuickView for CYP11B (gene)


Gene Symbol:
CYP11B1 Homo sapiens Homo sapiens
Full name:
cytochrome P450 family 11 subfamily B member 1
Synonyms:
CPN1, CYP11B, FHI, P450C11, cytochrome P450 11B1, mitochondrial, CYPXIB1, cytochrome P-450c11, cytochrome P450, family 11, subfamily B, polypeptide 1, cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1, cytochrome P450C11, cytochrome p450 XIB1, steroid 11-beta-hydroxylase, steroid 11-beta-monooxygenase
Genomic Location:
Chr 8: 143950775-143958238
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to c...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta
External Links:
Entrez Gene
Cytogenetic Map:
chr 8
8q24.3


Transcripts Names
NM_000497
NM_001026213



GO Molecular Function

cofactor binding | cation binding | steroid hydroxylase activity | iron ion binding | corticosterone 18-monooxygenase activity | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | tetrapyrrole binding | transition metal ion binding | heme binding | steroid 11-beta-monooxygenase activity | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

response to hormone | response to potassium ion | response to metal ion | glucose homeostasis | sterol metabolic process | cellular process | cellular response to potassium ion | response to inorganic substance | response to peptide hormone | steroid hydroxylase activity | organic cyclic compound metabolic process | cellular response to organonitrogen compound | steroid biosynthetic process | cellular response to metal ion | response to stimulus | corticosterone 18-monooxygenase activity | alcohol metabolic process | response to peptide | cellular response to inorganic substance | blood circulation | cellular biosynthetic process | organic hydroxy compound metabolic process | response to nitrogen compound | cellular response to hormone stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | cellular response to peptide hormone stimulus | hormone biosynthetic process | lipid metabolic process | regulation of hormone levels | cellular response to peptide | regulation of blood pressure | small molecule metabolic process | cellular ketone metabolic process | biosynthetic process | lipid biosynthetic process | mineralocorticoid biosynthetic process | homeostatic process | drug metabolic process | cellular aldehyde metabolic process | response to organic substance | cortisol metabolic process | metabolic process | cholesterol metabolic process | oxidation-reduction process | chemical homeostasis | immune response | organic substance metabolic process | C21-steroid hormone metabolic process | steroid metabolic process | glucocorticoid metabolic process | hormone metabolic process | C21-steroid hormone biosynthetic process | glucocorticoid biosynthetic process | steroid 11-beta-monooxygenase activity | response to organonitrogen compound | aldosterone biosynthetic process | immune system process | cellular metabolic process | cellular response to organic substance | oxidoreductase activity | carbohydrate homeostasis | cortisol biosynthetic process | multicellular organismal process

GO Cellular Component

organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane