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QuickView for CYP21A2 (gene)

Gene Symbol:
CYP21A2 Homo sapiens Homo sapiens
Full name:
cytochrome P450 family 21 subfamily A member 2
CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B, steroid 21-hydroxylase, 21-OHase, cytochrome P450 XXI, cytochrome P450, family 21, subfamily A, polypeptide 2, cytochrome P450, subfamily XXIA (steroid 21-hydroxylase, congenital adrenal hyperplasia), polypeptide 2, cytochrome P450-C21B, steroid 21 hydroxylase, steroid 21-monooxygenase
Genomic Location:
Chr 6: 32114061-32117398
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is...
Mus musculus Macaca mulatta Bos taurus Canis lupus familiaris Gallus gallus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 6

GO Molecular Function

cofactor binding | cation binding | steroid 21-monooxygenase activity | steroid hydroxylase activity | lipid binding | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | tetrapyrrole binding | transition metal ion binding | heme binding | steroid binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

sterol metabolic process | cellular process | steroid 21-monooxygenase activity | steroid hydroxylase activity | organic cyclic compound metabolic process | steroid biosynthetic process | organic hydroxy compound metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | hormone biosynthetic process | lipid metabolic process | regulation of hormone levels | biosynthetic process | lipid biosynthetic process | mineralocorticoid biosynthetic process | metabolic process | oxidation-reduction process | organic substance metabolic process | steroid metabolic process | glucocorticoid metabolic process | hormone metabolic process | glucocorticoid biosynthetic process | cellular metabolic process | oxidoreductase activity

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane