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QuickView for CYP2J2;jsessionid=5B4BAB496B1F3AAEDB44A6F2C495DE16 (gene)


Gene Symbol:
CYP2J2 Homo sapiens Homo sapiens
Full name:
cytochrome P450 family 2 subfamily J member 2
Synonyms:
CPJ2, CYPIIJ2, cytochrome P450 2J2, arachidonic acid epoxygenase, cytochrome P450, family 2, subfamily J, polypeptide 2, cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2, flavoprotein-linked monooxygenase, microsomal monooxygenase
Genomic Location:
Chr 1: 60131568-60165011
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for e...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1p32.1


Transcripts Names
NM_000775
NR_134982
NR_134981
Protein Names
P51589



GO Molecular Function

cofactor binding | cation binding | steroid hydroxylase activity | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | linoleic acid epoxygenase activity | arachidonic acid monooxygenase activity | tetrapyrrole binding | transition metal ion binding | arachidonic acid 11,12-epoxygenase activity | heme binding | metal ion binding | arachidonic acid 14,15-epoxygenase activity | heterocyclic compound binding | oxidoreductase activity | aromatase activity | arachidonic acid epoxygenase activity

GO Biological Process

response to drug | cellular process | xenobiotic metabolic process | catabolic process | steroid hydroxylase activity | cellular lipid metabolic process | response to stimulus | monocarboxylic acid metabolic process | cellular response to xenobiotic stimulus | regulation of blood circulation | drug catabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | small molecule metabolic process | exogenous drug catabolic process | response to xenobiotic stimulus | regulation of heart contraction | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | linoleic acid epoxygenase activity | long-chain fatty acid metabolic process | arachidonic acid monooxygenase activity | drug metabolic process | carboxylic acid metabolic process | metabolic process | oxidation-reduction process | organic substance metabolic process | fatty acid metabolic process | icosanoid metabolic process | arachidonic acid 11,12-epoxygenase activity | organic acid metabolic process | linoleic acid metabolic process | epoxygenase P450 pathway | arachidonic acid 14,15-epoxygenase activity | cellular metabolic process | oxidoreductase activity | aromatase activity | arachidonic acid metabolic process | arachidonic acid epoxygenase activity

GO Cellular Component

intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | intracellular | membrane