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QuickView for CYP4F2 (gene)


Gene Symbol:
CYP4F2 Homo sapiens Homo sapiens
Full name:
cytochrome P450 family 4 subfamily F member 2
Synonyms:
CPF2, phylloquinone omega-hydroxylase CYP4F2, 20-HETE synthase, 20-hydroxyeicosatetraenoic acid synthase, CYPIVF2, arachidonic acid omega-hydroxylase, cytochrome P450 4F2, cytochrome P450, family 4, subfamily F, polypeptide 2, cytochrome P450, subfamily IVF, polypeptide 2, cytochrome P450-LTB-omega, leukotriene-B(4) 20-monooxygenase 1, leukotriene-B(4) omega-hydroxylase 1
Genomic Location:
Chr 19: 15849834-15869884
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 19
19p13.12


Transcripts Names
NM_001082



GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | cofactor binding | arachidonic acid omega-hydroxylase activity | cation binding | 20-aldehyde-leukotriene B4 20-monooxygenase activity | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | tocopherol omega-hydroxylase activity | tocotrienol omega-hydroxylase activity | arachidonic acid monooxygenase activity | tetrapyrrole binding | protein binding | alpha-tocopherol omega-hydroxylase activity | transition metal ion binding | alkane 1-monooxygenase activity | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | 20-hydroxy-leukotriene B4 omega oxidase activity | leukotriene-B4 20-monooxygenase activity | arachidonic acid epoxygenase activity

GO Biological Process

vitamin K catabolic process | oxidoreductase activity, acting on CH-OH group of donors | leukotriene metabolic process | regulation of localization | renal water homeostasis | arachidonic acid omega-hydroxylase activity | regulation of lipid transport | cellular process | organic substance catabolic process | hemostasis | negative regulation of secretion | omega-hydroxylase P450 pathway | catabolic process | organic cyclic compound metabolic process | cellular lipid metabolic process | 20-aldehyde-leukotriene B4 20-monooxygenase activity | long-chain fatty acid catabolic process | response to stimulus | monocarboxylic acid metabolic process | carboxylic acid catabolic process | response to stress | multicellular organismal homeostasis | very long-chain fatty acid metabolic process | fatty acid catabolic process | negative regulation of transport | blood circulation | cofactor metabolic process | metal ion homeostasis | blood coagulation | water homeostasis | organic hydroxy compound metabolic process | sodium ion homeostasis | positive regulation of icosanoid secretion | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | wound healing | positive regulation of secretion | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | regulation of blood pressure | ketone catabolic process | regulation of systemic arterial blood pressure | pressure natriuresis | small molecule metabolic process | menaquinone catabolic process | leukotriene B4 catabolic process | vitamin K metabolic process | cellular ketone metabolic process | negative regulation of ion transport | positive regulation of lipid localization | cation homeostasis | tocopherol omega-hydroxylase activity | cellular lipid catabolic process | homeostatic process | positive regulation of transport | coagulation | long-chain fatty acid metabolic process | tocotrienol omega-hydroxylase activity | arachidonic acid monooxygenase activity | drug metabolic process | carboxylic acid metabolic process | alpha-tocopherol omega-hydroxylase activity | negative regulation of lipid transport | vitamin metabolic process | response to wounding | vitamin E metabolic process | metabolic process | negative regulation of fatty acid transport | regulation of body fluid levels | oxidation-reduction process | chemical homeostasis | regulation of secretion | lipid catabolic process | organic substance metabolic process | positive regulation of ion transport | ion homeostasis | renal system process | fatty acid metabolic process | positive regulation of organic acid transport | phylloquinone catabolic process | negative regulation of icosanoid secretion | icosanoid metabolic process | alkane 1-monooxygenase activity | organic acid metabolic process | epoxygenase P450 pathway | regulation of ion transport | renal system process involved in regulation of systemic arterial blood pressure | positive regulation of anion transport | regulation of transport | quinone metabolic process | regulation of fatty acid transport | multicellular organismal water homeostasis | heterocycle metabolic process | regulation of anion transport | positive regulation of lipid transport | cellular metabolic process | oxidoreductase activity | 20-hydroxy-leukotriene B4 omega oxidase activity | arachidonic acid metabolic process | leukotriene-B4 20-monooxygenase activity | arachidonic acid epoxygenase activity | positive regulation of fatty acid transport | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | apical plasma membrane | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | apical part of cell | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane