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QuickView for CYP51A1 (gene)


Gene Symbol:
CYP51A1 Homo sapiens Homo sapiens
Full name:
cytochrome P450 family 51 subfamily A member 1
Synonyms:
CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1, lanosterol 14-alpha demethylase, CYPLI, cytochrome P450 51A1, cytochrome P450, 51 (lanosterol 14-alpha-demethylase), cytochrome P450, family 51, subfamily A, polypeptide 1, cytochrome P450-14DM, cytochrome P45014DM, cytochrome P450LI, sterol 14-alpha demethylase
Genomic Location:
Chr 7: 91579402-91601946
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the ...
Orthologs:
Mus musculus Rattus norvegicus Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 7
7q21.2





GO Molecular Function

cofactor binding | sterol 14-demethylase activity | cation binding | iron ion binding | demethylase activity | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

sterol 14-demethylase activity | sterol metabolic process | regulation of metabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | demethylase activity | alcohol metabolic process | regulation of steroid biosynthetic process | regulation of steroid metabolic process | organic hydroxy compound metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | regulation of cholesterol biosynthetic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | sterol biosynthetic process | small molecule metabolic process | regulation of cholesterol metabolic process | biosynthetic process | cholesterol biosynthetic process | lipid biosynthetic process | regulation of lipid biosynthetic process | metabolic process | cholesterol metabolic process | oxidation-reduction process | cholesterol biosynthetic process via 24,25-dihydrolanosterol | organic substance metabolic process | steroid metabolic process | demethylation | regulation of lipid metabolic process | oxidoreductase activity

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane