QuickView for Cabin1 (gene)
- Gene Symbol:
- CABIN1
Homo sapiens - Full name:
- calcineurin binding protein 1
- Synonyms:
- CAIN, KB-318B8.7, PPP3IN, calcineurin-binding protein cabin-1, calcineurin binding protein cabin 1, calcineurin inhibitor
- Genomic Location:
- Chr 22: 22737765-22904596
- Description:
-
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST moti...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
22q11.23
GO Molecular Function
phosphatase inhibitor activity | nucleosome binding | protein-containing complex binding | enzyme inhibitor activity | molecular function regulator | chromatin binding | protein phosphatase regulator activity | protein phosphatase inhibitor activity | enzyme regulator activity | phosphatase regulator activity
GO Biological Process
phosphatase inhibitor activity | regulation of dephosphorylation | nucleosome organization | negative regulation of cellular process | regulation of phosphatase activity | cellular process | chromatin organization | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | negative regulation of phosphatase activity | cellular component organization | response to stimulus | enzyme inhibitor activity | protein-DNA complex assembly | negative regulation of metabolic process | cellular component assembly | molecular function regulator | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of catalytic activity | DNA replication-independent nucleosome assembly | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | cellular protein-containing complex assembly | negative regulation of protein dephosphorylation | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | protein-containing complex assembly | regulation of protein dephosphorylation | chromatin assembly or disassembly | cell surface receptor signaling pathway | negative regulation of cellular protein metabolic process | protein phosphatase regulator activity | regulation of phosphate metabolic process | DNA packaging | chromatin assembly | negative regulation of protein metabolic process | protein phosphatase inhibitor activity | negative regulation of molecular function | signaling | enzyme regulator activity | negative regulation of phosphoprotein phosphatase activity | regulation of phosphoprotein phosphatase activity | organelle organization | DNA replication-independent nucleosome organization | DNA conformation change | negative regulation of dephosphorylation | negative regulation of hydrolase activity | nucleosome assembly | chromosome organization | phosphatase regulator activity | signal transduction | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | inclusion body | nucleoplasm | membrane-bounded organelle | aggresome | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
