QuickView for Cadps (gene)

Gene Symbol:

CADPS Homo sapiens

Full name:

calcium dependent secretion activator

Synonyms:

CADPS1, CAPS, CAPS1, UNC-31, calcium-dependent secretion activator 1, CAPS-1, Ca++-dependent secretion activator, Ca2+ dependent secretion activator, Ca2+-dependent activator protein for secretion, Ca2+-regulated cytoskeletal protein, calcium-dependent activator protein for secretion 1

Genomic Location:

Chr 3: 62359061-62836094

Description:

This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative spl...

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This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  TCANNTGAY_SREBP1_01 ,  FOX_Q2 ,  FOXO4_01 ,  GCANCTGNY_MYOD_Q6 ,  XBP1_01 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  CTTTGA_LEF1_Q2 ,  AAGCAAT_MIR137 ,  ATCTTGC_MIR31 ,  HEB_Q6 ,  GGGAGGRR_MAZ_Q6 ,  SOX9_B1 ,  AP4_Q6 ,  TGCCTTA_MIR124A ,  GGGCGGR_SP1_Q6 ,  FOXO1_01 ,  MTF1_Q4 ,  AP4_Q6_01 ,  CCANNAGRKGGC_UNKNOWN ,  CAGCTG_AP4_Q5 ,  SMAD_Q6 ,  AACTTT_UNKNOWN ,  PAX2_02

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-494 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-409-5p ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-496

Cytogenetic Map:

3p14.2

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