Bookmark
Forward
Export Results
QuickView for Calponin repeat (biogroup)
- Description:
- Calponin is a thin filament-associated protein that is implicated in the regulationand modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C andtropomyosin. The interaction of calponin with actin inhibits the actomyosin MgATPase activity. Calponin is abasic protein of approximately 34 Kd. Multiple isoforms are found in smooth muscles. Calponin contains threerepeats of a well conserved 26 amino acid domain. Such a domain is also found in vertebrate smooth muscle protein(SM22 or transgelin), and a number of other proteins whose physiological role is not yet established, includingDrosophila synchronous flight muscle protein SM20, Caenorhabditis elegans unc-87 protein, rat neuronal protein NP25, and an Onchocerca volvulus antigen.
SELECTED ORGANISM:
