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QuickView for Cdc7 (gene)


Gene Symbol:
CDC7 Homo sapiens Homo sapiens
Full name:
cell division cycle 7
Synonyms:
CDC7L1, HsCDC7, Hsk1, huCDC7, cell division cycle 7-related protein kinase, CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1, CDC7-related kinase, cell division cycle 7 homolog, cell division cycle 7-like protein 1
Genomic Location:
Chr 1: 91739032-91763902
Description:
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript ...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Schizosaccharomyces pombe Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1p22.1





GO Molecular Function

cation binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

double-strand break repair | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | peptidyl-amino acid modification | regulation of nuclear cell cycle DNA replication | positive regulation of G2/M transition of mitotic cell cycle | negative regulation of cellular process | regulation of DNA replication | positive regulation of cellular biosynthetic process | cellular process | double-strand break repair via break-induced replication | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of nuclear cell cycle DNA replication | positive regulation of cell cycle phase transition | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | regulation of G2/M transition of mitotic cell cycle | DNA-dependent DNA replication | DNA replication initiation | response to stimulus | peptidyl-threonine phosphorylation | regulation of mitotic cell cycle phase transition | response to stress | regulation of cell proliferation | regulation of cell cycle phase transition | protein serine/threonine kinase activity | cellular nitrogen compound metabolic process | cell cycle G1/S phase transition | protein modification process | cellular biosynthetic process | DNA recombination | macromolecule modification | DNA repair | regulation of cell cycle G2/M phase transition | nitrogen compound metabolic process | double-strand break repair via homologous recombination | positive regulation of DNA replication | phosphorus metabolic process | cellular response to DNA damage stimulus | positive regulation of cell cycle | positive regulation of mitotic cell cycle | cellular response to stress | cell cycle | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of cell cycle G2/M phase transition | negative regulation of G0 to G1 transition | biosynthetic process | cell division | phosphorylation | regulation of DNA-dependent DNA replication | mitotic cell cycle phase transition | protein phosphorylation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | G1/S transition of mitotic cell cycle | positive regulation of cell proliferation | regulation of mitotic cell cycle | protein metabolic process | DNA metabolic process | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | metabolic process | nucleobase-containing compound metabolic process | protein kinase activity | positive regulation of DNA-dependent DNA replication | organic substance metabolic process | regulation of G0 to G1 transition | negative regulation of cell cycle | cellular protein metabolic process | cellular macromolecule biosynthetic process | positive regulation of DNA metabolic process | kinase activity | recombinational repair | positive regulation of cell cycle process | peptidyl-serine phosphorylation | cellular protein modification process | cell cycle phase transition | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | negative regulation of cell cycle process | DNA replication | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | intercellular bridge | cytoplasm | spindle | intracellular organelle | nucleoplasm | microtubule cytoskeleton | extracellular region | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytoskeleton | intracellular | mitotic spindle