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QuickView for Cefradine (compound)


PubChem
Name: Cephradine
PubChem Compound ID: 10670927
Description: A semi-synthetic cephalosporin antibiotic.
Molecular formula: C24H45NO6
Molecular weight: 443.617 g/mol
DrugBank
Identification
Name: Cephradine
Name (isomeric): DB01333
Drug Type: small molecule
Description: A semi-synthetic cephalosporin antibiotic.
Synonyms:
Cephradine
Category: Cephalosporins, Anti-Bacterial Agents
CAS number: 38821-53-3
Pharmacology
Mechanism of Action:
Cefradine is a first generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin. Cefradine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis i...
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Route of elimination: Over 90 percent of the drug is excreted unchanged in the urine within six hours.
Interactions
Drug interaction:
ProbenecidProbenecid may increase the serum level of cefradine.
TobramycinIncreased risk of nephrotoxicity
AmikacinIncreased risk of nephrotoxicity
NetilmicinIncreased risk of nephrotoxicity
GentamicinIncreased risk of nephrotoxicity

Targets


Transporters