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QuickView for Chrna2 (gene)


Gene Symbol:
CHRNA2 Homo sapiens Homo sapiens
Full name:
cholinergic receptor nicotinic alpha 2 subunit
Synonyms:
neuronal acetylcholine receptor subunit alpha-2, acetylcholine receptor, nicotinic, alpha 2 (neuronal), cholinergic receptor, nicotinic alpha 2, cholinergic receptor, nicotinic, alpha 2 (neuronal), cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
Genomic Location:
Chr 8: 27373195-27392730
Description:
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha s...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 8
8p21.2





GO Molecular Function

transmitter-gated ion channel activity | acetylcholine-gated cation-selective channel activity | neurotransmitter receptor activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | cation transmembrane transporter activity | acetylcholine receptor activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | excitatory extracellular ligand-gated ion channel activity | cation channel activity | inorganic cation transmembrane transporter activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

transmitter-gated ion channel activity | acetylcholine-gated cation-selective channel activity | establishment of localization | excitatory postsynaptic potential | cellular process | localization | passive transmembrane transporter activity | chemical synaptic transmission | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | cellular component organization | response to stimulus | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | cellular component assembly | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | regulation of membrane potential | protein complex oligomerization | ion transmembrane transport | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | cation transmembrane transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | cell communication | cation transmembrane transport | protein-containing complex assembly | cell surface receptor signaling pathway | excitatory extracellular ligand-gated ion channel activity | cation channel activity | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | protein heterooligomerization | cation transport | channel activity | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | synapse | neuron projection | cell | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | receptor complex | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | integral component of plasma membrane | cell periphery | transmembrane transporter complex | ion channel complex | cell junction | acetylcholine-gated channel complex | membrane | intrinsic component of plasma membrane