Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for ClpX (gene)


Gene Symbol:
CLPX Homo sapiens Homo sapiens
Full name:
caseinolytic mitochondrial matrix peptidase chaperone subunit
Synonyms:
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, ClpX caseinolytic peptidase X homolog, ClpX caseinolytic protease X homolog, energy-dependent regulator of proteolysis
Genomic Location:
Chr 15: 63229837-63264616
Description:
The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by...
Orthologs:
Mus musculus Rattus norvegicus Saccharomyces cerevisiae Macaca mulatta Bos taurus Gallus gallus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 15
15q22.31





GO Molecular Function

enzyme activator activity | ATP-dependent peptidase activity | cation binding | ribonucleotide binding | peptidase activator activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | unfolded protein binding | ATPase activity | pyrophosphatase activity | molecular function regulator | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | metal ion binding | heterocyclic compound binding | peptidase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | enzyme activator activity | proteolysis | ATP-dependent peptidase activity | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | nucleotide metabolic process | ribose phosphate metabolic process | regulation of proteolysis | nucleoside triphosphate metabolic process | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | ribonucleotide metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | peptidase activator activity | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular aromatic compound metabolic process | purine nucleotide metabolic process | positive regulation of protein metabolic process | positive regulation of peptidase activity | cellular protein catabolic process | positive regulation of proteolysis | cellular nitrogen compound metabolic process | molecular function regulator | nitrogen compound metabolic process | regulation of peptidase activity | phosphorus metabolic process | regulation of catalytic activity | protein catabolic process | organophosphate metabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | positive regulation of hydrolase activity | nucleobase-containing small molecule metabolic process | regulation of cellular protein metabolic process | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of protein metabolic process | drug metabolic process | positive regulation of molecular function | protein metabolic process | cellular macromolecule catabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | protein folding | organonitrogen compound catabolic process | cellular protein metabolic process | enzyme regulator activity | carbohydrate derivative metabolic process | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | peptidase activity | ATP metabolic process | macromolecule metabolic process

GO Cellular Component

endopeptidase Clp complex | mitochondrial matrix | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | nuclear lumen | mitochondrial nucleoid | mitochondrial endopeptidase Clp complex | cytoplasm | nucleoid | intracellular organelle | protein-containing complex | nucleoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial envelope | membrane-enclosed lumen | mitochondrial membrane | cytosol | intracellular | membrane