QuickView for CtBP1 (gene)

Gene Symbol:

CTBP1 Homo sapiens

Full name:

C-terminal binding protein 1

Synonyms:

BARS, C-terminal-binding protein 1, brefeldin A-ribosylated substrate

Genomic Location:

Chr 4: 1195228-1232908

Description:

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which par...

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This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GAGACTG_MIR452 ,  TGTATGA_MIR4853P ,  CAGGTG_E12_Q6 ,  ACCATTT_MIR522

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-137

Cytogenetic Map:

4p16.3

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