Correlation Engine 2.0
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QuickView for DAP5 (gene)

Gene Symbol:
EIF4G2 Homo sapiens Homo sapiens
Full name:
eukaryotic translation initiation factor 4 gamma 2
AAG1, DAP5, NAT1, P97, eukaryotic translation initiation factor 4 gamma 2, DAP-5, aging-associated protein 1, death-associated protein 5, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, eukaryotic translation initiation factor 4G-like 1
Genomic Location:
Chr 11: 10775169-10787158
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites...
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for let-7 Predicted Gene Targets for miR-101 Predicted Gene Targets for miR-139 Predicted Gene Targets for miR-144 Predicted Gene Targets for miR-146 Predicted Gene Targets for miR-19 Predicted Gene Targets for miR-194 Predicted Gene Targets for miR-20 Predicted Gene Targets for miR-208 Predicted Gene Targets for miR-25
Cytogenetic Map:
chr 11

GO Molecular Function

cadherin binding | nucleic acid binding | mRNA binding | translation initiation factor activity | translation factor activity, RNA binding | organic cyclic compound binding | cell adhesion molecule binding | protein binding | heterocyclic compound binding | RNA binding

GO Biological Process

regulation of autophagy | negative regulation of cellular process | cellular process | regulation of cell cycle | negative regulation of cellular metabolic process | regulation of cellular process | positive regulation of cell growth | regulation of metabolic process | regulation of translational initiation | peptide biosynthetic process | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | translation initiation factor activity | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | translational initiation | nitrogen compound metabolic process | regulation of gene expression | cell cycle | regulation of nitrogen compound metabolic process | cellular amide metabolic process | translation | translation factor activity, RNA binding | biosynthetic process | regulation of cellular protein metabolic process | negative regulation of autophagy | regulation of cellular metabolic process | regulation of protein metabolic process | peptide metabolic process | protein metabolic process | regulation of growth | cell cycle arrest | metabolic process | organic substance metabolic process | cell death | gene expression | amide biosynthetic process | negative regulation of cell cycle | positive regulation of growth | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of cell growth | cellular metabolic process | regulation of translation | regulation of cellular component organization | macromolecule metabolic process

GO Cellular Component

adherens junction | cell | cytoplasm | cell-cell adherens junction | cell-cell junction | eukaryotic translation initiation factor 4F complex | protein-containing complex | cytosol | intracellular | cell junction | membrane