QuickView for DAX1 (gene)

Gene Symbol:

NR0B1 Homo sapiens

Full name:

nuclear receptor subfamily 0 group B member 1

Synonyms:

AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1, SRXY2, nuclear receptor subfamily 0 group B member 1, DSS-AHC critical region on the X chromosome protein 1, nuclear hormone receptor, nuclear receptor DAX-1, truncated nuclear receptor subfamily 0 group B member 1

Genomic Location:

Chr X: 30232506-30237413

Description:

This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia...

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This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGACCTY_ERR1_Q2 ,  TATAAA_TATA_01 ,  AHR_Q5 ,  TBP_01 ,  RCGCANGCGY_NRF1_Q6

Cytogenetic Map:

Xp21.2

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