Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for DBP-RB (gene)


Gene Symbol:
DDX1 Homo sapiens Homo sapiens
Full name:
DEAD-box helicase 1
Synonyms:
DBP-RB, UKVH5d, ATP-dependent RNA helicase DDX1, DEAD (Asp-Glu-Ala-Asp) box helicase 1, DEAD (Asp-Glu-Ala-Asp) box polypeptide 1, DEAD box polypeptide 1, DEAD box protein 1, DEAD box protein retinoblastoma, DEAD box-1, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1, DEAD/H-box helicase 1
Genomic Location:
Chr 2: 15649221-15688676
Description:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patte...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2p24.3


Transcripts Names
NM_004939
Protein Names
A3RJH1
Q92499



GO Molecular Function

nuclease activity | nucleic acid binding | ribonucleotide binding | poly(A) binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | chromatin binding | ATP binding | anion binding | adenyl nucleotide binding | single-stranded RNA binding | DNA/RNA helicase activity | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | poly-purine tract binding | protein binding | RNA helicase activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | helicase activity | drug binding | exonuclease activity | transcription coregulator activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | RNA binding | double-stranded RNA binding

GO Biological Process

RNA metabolic process | double-strand break repair | protein localization to cytoplasmic stress granule | response to virus | RNA processing | nuclease activity | cellular process | response to exogenous dsRNA | localization | macromolecule localization | DNA geometric change | regulation of cellular process | regulation of metabolic process | spliceosomal complex assembly | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | regulation of translational initiation | response to stimulus | RNA splicing | response to stress | RNA splicing, via transesterification reactions | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | ncRNA processing | cellular localization | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | cellular component assembly | mRNA metabolic process | cellular biosynthetic process | DNA repair | regulation of nucleic acid-templated transcription | tRNA splicing, via endonucleolytic cleavage and ligation | response to nitrogen compound | response to external biotic stimulus | nitrogen compound metabolic process | multicellular organism development | response to dsRNA | cellular response to DNA damage stimulus | regulation of gene expression | cellular response to stress | regulation of nitrogen compound metabolic process | protein localization to organelle | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | cellular protein-containing complex assembly | DNA duplex unwinding | regulation of cellular metabolic process | regulation of protein metabolic process | tRNA processing | regulation of RNA metabolic process | tRNA metabolic process | protein-containing complex assembly | response to organic substance | DNA metabolic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | cellular protein localization | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | ribonucleoprotein complex assembly | transcription, DNA-templated | regulation of transcription, DNA-templated | response to organic cyclic compound | protein localization | cellular macromolecule localization | cellular macromolecule biosynthetic process | response to biotic stimulus | developmental process | organelle organization | exonuclease activity | ncRNA metabolic process | DNA conformation change | transcription coregulator activity | heterocycle metabolic process | chromosome organization | ribonucleoprotein complex biogenesis | cellular metabolic process | mRNA processing | regulation of translation | mRNA splicing, via spliceosome | response to other organism | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cytoplasmic stress granule | cell | nuclear lumen | ribonucleoprotein granule | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | cleavage body | ribonucleoprotein complex | membrane-bounded organelle | tRNA-splicing ligase complex | nucleus | organelle | cytoplasmic ribonucleoprotein granule | membrane-enclosed lumen | cytosol | intracellular | membrane