QuickView for DDX5 (gene)

Gene Symbol:

DDX5 Homo sapiens

Full name:

DEAD-box helicase 5

Synonyms:

G17P1, HLR1, HUMP68, p68, probable ATP-dependent RNA helicase DDX5, ATP-dependent RNA helicase DDX5, DEAD (Asp-Glu-Ala-Asp) box helicase 5, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, DEAD box protein 5, DEAD box-5, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD), RNA helicase p68

Genomic Location:

Chr 17: 59926200-59932869

Description:

This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of tran...

View Full Description

This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

FOXO1_02 ,  GABP_B ,  RTAAACA_FREAC2_01 ,  SMTTTTGT_UNKNOWN ,  TFIIA_Q6 ,  HOXA4_Q2 ,  CACGTG_MYC_Q2 ,  E4BP4_01 ,  CAGTGTT_MIR141_MIR200A ,  TTAYRTAA_E4BP4_01 ,  WHN_B ,  GGGAGGRR_MAZ_Q6 ,  TATAAA_TATA_01 ,  ACATTCC_MIR1_MIR206 ,  YYCATTCAWW_UNKNOWN ,  TATA_C ,  ZID_01 ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  CATRRAGC_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  S8_01 ,  ACTGCAG_MIR173P ,  GGCNNMSMYNTTG_UNKNOWN ,  KCCGNSWTTT_UNKNOWN ,  HLF_01 ,  AP2_Q6 ,  SCGGAAGY_ELK1_02 ,  TATA_01 ,  IK1_01 ,  NRF2_01 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  ACAWNRNSRCGG_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  EGR1_01 ,  CAGCTG_AP4_Q5 ,  ELK1_02 ,  GCTNWTTGK_UNKNOWN ,  GGCAGTG_MIR3243P ,  TCF1P_Q6 ,  ATGAAGG_MIR205

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-205 ,  Predicted Gene Targets for miR-324-3p ,  Predicted Gene Targets for miR-325 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-496 ,  Predicted Gene Targets for miR-544

miRNA binding sites
(Source: miRecords):

hsa-miR-1 Targeted Genes

Cytogenetic Map:

17q23.3

search → result