Correlation Engine 2.0
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QuickView for DGKA (gene)

Gene Symbol:
DGKA Homo sapiens Homo sapiens
Full name:
diacylglycerol kinase alpha
DAGK, DAGK1, DGK-alpha, diacylglycerol kinase alpha, 80 kDa diacylglycerol kinase, DAG kinase alpha, diacylglycerol kinase, alpha 80kDa, diglyceride kinase alpha
Genomic Location:
Chr 12: 54611213-54634074
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidi...
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 12

GO Molecular Function

cation binding | ribonucleotide binding | lipid binding | nucleotide binding | carbohydrate derivative binding | phospholipid binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | diacylglycerol kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | transferase activity | calcium ion binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | NAD+ kinase activity | small molecule binding

GO Biological Process

intracellular signal transduction | phospholipid metabolic process | cellular process | hemostasis | regulation of cellular process | cellular lipid metabolic process | response to stimulus | response to stress | G-protein coupled receptor signaling pathway | cellular biosynthetic process | blood coagulation | phosphatidic acid metabolic process | phosphorus metabolic process | lipid metabolic process | wound healing | platelet activation | organophosphate metabolic process | phospholipid biosynthetic process | biosynthetic process | phosphorylation | lipid biosynthetic process | phosphate-containing compound metabolic process | lipid phosphorylation | cell communication | lipid modification | protein kinase C-activating G-protein coupled receptor signaling pathway | glycerolipid metabolic process | coagulation | diacylglycerol metabolic process | neutral lipid metabolic process | glycerophospholipid biosynthetic process | response to wounding | diacylglycerol kinase activity | metabolic process | regulation of body fluid levels | organic substance metabolic process | cell activation | signaling | glycerophospholipid metabolic process | kinase activity | phosphatidic acid biosynthetic process | cellular metabolic process | acylglycerol metabolic process | NAD+ kinase activity | signal transduction | multicellular organismal process

GO Cellular Component

cell | cytoplasm | plasma membrane | cell periphery | cytosol | intracellular | membrane