QuickView for DGKI;jsessionid=851C9E7D347AA3D49E84C243D61FDCA6 (gene)
- Gene Symbol:
- DGKI
Homo sapiens - Full name:
- diacylglycerol kinase iota
- Synonyms:
- DGK-IOTA, diacylglycerol kinase iota, DAG kinase iota, diglyceride kinase iota
- Genomic Location:
- Chr 7: 136724925-137182149
- Description:
-
This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidi...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
7q33
GO Molecular Function
GTPase binding | cation binding | enzyme binding | ribonucleotide binding | nucleotide binding | enzyme inhibitor activity | GTPase regulator activity | carbohydrate derivative binding | Ras GTPase binding | molecular function regulator | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | diacylglycerol kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | transferase activity | small GTPase binding | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | GTPase inhibitor activity | NAD+ kinase activity | small molecule binding
GO Biological Process
positive regulation of Ras protein signal transduction | neurotransmitter secretion | intracellular signal transduction | establishment of localization | excitatory postsynaptic potential | cellular process | secretion | localization | chemical synaptic transmission | habituation | learning | hemostasis | establishment of localization in cell | regulation of cellular process | cellular lipid metabolic process | response to stimulus | enzyme inhibitor activity | GTPase regulator activity | response to stress | cellular localization | secretion by cell | G-protein coupled receptor signaling pathway | modulation of chemical synaptic transmission | cell-cell signaling | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | blood coagulation | regulation of membrane potential | regulation of neurotransmitter levels | regulation of signal transduction | negative regulation of catalytic activity | regulation of synaptic transmission, glutamatergic | phosphorus metabolic process | learning or memory | regulation of catalytic activity | lipid metabolic process | wound healing | nonassociative learning | regulation of small GTPase mediated signal transduction | platelet activation | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | positive regulation of intracellular signal transduction | cognition | phosphorylation | regulation of GTPase activity | phosphate-containing compound metabolic process | lipid phosphorylation | regulation of long term synaptic depression | cell communication | positive regulation of signal transduction | lipid modification | protein kinase C-activating G-protein coupled receptor signaling pathway | coagulation | response to wounding | diacylglycerol kinase activity | regulation of intracellular signal transduction | cell surface receptor signaling pathway | positive regulation of small GTPase mediated signal transduction | metabolic process | regulation of body fluid levels | behavior | organic substance metabolic process | cell activation | regulation of cell communication | negative regulation of molecular function | signaling | enzyme regulator activity | regulation of Ras protein signal transduction | kinase activity | neurotransmitter transport | signal release | negative regulation of GTPase activity | negative regulation of hydrolase activity | regulation of synaptic plasticity | cellular metabolic process | GTPase inhibitor activity | NAD+ kinase activity | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process
GO Cellular Component
dendritic spine | exocytic vesicle | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | nuclear lumen | neuronal cell body | distal axon | synaptic membrane | cytoplasm | intracellular organelle | dendritic tree | presynapse | protein-containing complex | cell projection | secretory vesicle | endomembrane system | neuron spine | postsynapse | nucleoplasm | plasma membrane | guanyl-nucleotide exchange factor complex | vesicle | transport vesicle | perinuclear region of cytoplasm | postsynaptic density | asymmetric synapse | synaptic vesicle | membrane-bounded organelle | nucleus | organelle | postsynaptic specialization | axon terminus | presynaptic active zone | cell periphery | excitatory synapse | axon | membrane-enclosed lumen | neuron projection terminus | cytosol | intracellular vesicle | intracellular | membrane
