Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for DHRS2 (gene)


Gene Symbol:
DHRS2 Homo sapiens Homo sapiens
Full name:
dehydrogenase/reductase 2
Synonyms:
HEP27, SDR25C1, dehydrogenase/reductase SDR family member 2, mitochondrial, dehydrogenase/reductase (SDR family) member 2, dehydrogenase/reductase member 2, dicarbonyl reductase HEP27, protein D, short chain dehydrogenase/reductase family 25C member 1, short-chain alcohol dehydrogenase family member
Genomic Location:
Chr 14: 23175422-23184688
Description:
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family, which has over 46,000 members. Members of this family are enzymes that metabolize many different compounds, such as steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. Alternative promoter use and alternative splicing results in multiple transcrip...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 14
14q11.2





GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | catalytic activity | carbonyl reductase (NADPH) activity | protein binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | oxidoreductase activity

GO Biological Process

oxidoreductase activity, acting on CH-OH group of donors | regulation of programmed cell death | myeloid cell differentiation | negative regulation of cellular process | cell differentiation | cellular process | immune system development | negative regulation of apoptotic process | myeloid dendritic cell differentiation | regulation of cellular process | leukocyte activation | regulation of apoptotic process | organic cyclic compound metabolic process | response to stimulus | response to stress | regulation of cell proliferation | myeloid dendritic cell activation | hemopoiesis | leukocyte differentiation | system development | multicellular organism development | lipid metabolic process | cellular response to oxidative stress | regulation of hormone levels | cellular response to stress | myeloid leukocyte differentiation | response to oxidative stress | carbonyl reductase (NADPH) activity | response to toxic substance | anatomical structure development | metabolic process | dendritic cell differentiation | oxidation-reduction process | negative regulation of programmed cell death | organic substance metabolic process | animal organ development | C21-steroid hormone metabolic process | cell activation | steroid metabolic process | hormone metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | developmental process | negative regulation of cell proliferation | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | regulation of cell death | oxidoreductase activity | negative regulation of cell death | multicellular organismal process

GO Cellular Component

mitochondrial matrix | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endomembrane system | nuclear envelope | mitochondrion | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular