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QuickView for DHX33;jsessionid=E10958033198F1D4407FD5100F9BBB26 (gene)


Gene Symbol:
DHX33 Homo sapiens Homo sapiens
Full name:
DEAH-box helicase 33
Synonyms:
DDX33, putative ATP-dependent RNA helicase DHX33, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 33, DEAH (Asp-Glu-Ala-His) box polypeptide 33, DEAH box protein 33
Genomic Location:
Chr 17: 5286299-5312905
Description:
This gene encodes a member of the DEAD box protein family. The DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ri...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Cytogenetic Map:
chr 17
17p13.2





GO Molecular Function

sequence-specific DNA binding | ATP-dependent RNA helicase activity | 3'-5' RNA helicase activity | RNA-dependent ATPase activity | nucleic acid binding | protein-containing complex binding | ribonucleotide binding | mRNA binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP-dependent 3'-5' RNA helicase activity | ribonucleoprotein complex binding | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | sequence-specific double-stranded DNA binding | purine nucleotide binding | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | double-stranded DNA binding | transcription factor binding | activating transcription factor binding | RNA helicase activity | rDNA binding | hydrolase activity, acting on acid anhydrides | ribosomal large subunit binding | purine ribonucleotide binding | adenyl ribonucleotide binding | helicase activity | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | RNA binding | double-stranded RNA binding

GO Biological Process

positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | positive regulation of DNA-binding transcription factor activity | regulation of transcription by RNA polymerase I | positive regulation of phosphate metabolic process | positive regulation of cellular biosynthetic process | cellular process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | regulation of protein complex assembly | positive regulation of NLRP3 inflammasome complex assembly | positive regulation of cellular protein metabolic process | regulation of type I interferon production | peptide biosynthetic process | positive regulation of protein metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | translational initiation | regulation of nucleic acid-templated transcription | regulation of NLRP3 inflammasome complex assembly | nitrogen compound metabolic process | regulation of signal transduction | regulation of MAPK cascade | regulation of phosphorylation | regulation of gene expression | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | cellular amide metabolic process | translation | biosynthetic process | regulation of cellular protein metabolic process | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | peptide metabolic process | regulation of RNA metabolic process | positive regulation of molecular function | protein metabolic process | positive regulation of protein modification process | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | metabolic process | regulation of RNA biosynthetic process | positive regulation of cellular component biogenesis | organic substance metabolic process | gene expression | amide biosynthetic process | positive regulation of NF-kappaB transcription factor activity | positive regulation of transcription by RNA polymerase I | regulation of phosphate metabolic process | positive regulation of cytokine production | positive regulation of MAPK cascade | regulation of cell communication | regulation of transcription, DNA-templated | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | cellular macromolecule biosynthetic process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of metabolic process | cellular metabolic process | positive regulation of type I interferon production | regulation of cellular component organization | positive regulation of signaling | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

NLRP3 inflammasome complex | intracellular membrane-bounded organelle | cell | nuclear lumen | inflammasome complex | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular