QuickView for DLL4 (gene)

Gene Symbol:

DLL4 Homo sapiens

Full name:

delta like canonical Notch ligand 4

Synonyms:

AOS6, hdelta2, delta-like protein 4, delta 4, delta ligand 4, delta-like 4 homolog, delta-like 4 protein, delta4, drosophila Delta homolog 4, notch ligand DLL4, notch ligand delta-2

Genomic Location:

Chr 15: 39008839-39018529

Description:

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  SP1_01 ,  MAZR_01 ,  GAGCCTG_MIR484 ,  TAL1ALPHAE47_01 ,  ZIC1_01 ,  RYTTCCTG_ETS2_B ,  AREB6_02 ,  NFAT_Q6 ,  HEN1_01 ,  YATGNWAAT_OCT_C ,  YTATTTTNR_MEF2_02 ,  GCANCTGNY_MYOD_Q6 ,  E2F_Q6_01 ,  AP2GAMMA_01 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  TAAYNRNNTCC_UNKNOWN ,  ZIC3_01 ,  CTTTGA_LEF1_Q2 ,  AP2ALPHA_01 ,  MYCMAX_B ,  WHN_B ,  ACTGTGA_MIR27A_MIR27B ,  GGGAGGRR_MAZ_Q6 ,  YAATNRNNNYNATT_UNKNOWN ,  MEF2_02 ,  AR_Q6 ,  TAL1BETAE47_01 ,  GGGYGTGNY_UNKNOWN ,  MEF2_01 ,  GGATTA_PITX2_Q2 ,  RREB1_01 ,  STAT5B_01 ,  CAGGTG_E12_Q6 ,  CTCAGGG_MIR125B_MIR125A ,  LHX3_01 ,  EGR_Q6 ,  GGGCGGR_SP1_Q6 ,  AREB6_01 ,  CCCNNGGGAR_OLF1_01 ,  HIF1_Q5 ,  E47_01 ,  GCM_Q2 ,  E2F_03 ,  HMEF2_Q6 ,  AHRARNT_01 ,  GTGCCTT_MIR506 ,  TAATTA_CHX10_01 ,  GR_01 ,  AP4_Q6_01 ,  MYOGENIN_Q6 ,  CART1_01 ,  AFP1_Q6 ,  GATA4_Q3 ,  IRF7_01 ,  YTAATTAA_LHX3_01 ,  IK1_01 ,  ZIC2_01 ,  TTCYNRGAA_STAT5B_01 ,  TAL1BETAITF2_01 ,  AAGCACT_MIR520F ,  TGACAGNY_MEIS1_01 ,  STAT5A_01 ,  EGR1_01 ,  YRCCAKNNGNCGC_UNKNOWN ,  CAGCTG_AP4_Q5 ,  CDC5_01 ,  ZF5_B ,  AP4_Q5 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  PAX4_01 ,  CP2_01 ,  GGGTGGRR_PAX4_03 ,  TCCAGAG_MIR518C ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-124a

Cytogenetic Map:

15q15.1

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