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QuickView for DMPK (gene)

Gene Symbol:
DMPK Homo sapiens Homo sapiens
Full name:
DM1 protein kinase
DM, DM1, DM1PK, DMK, MDPK, MT-PK, myotonin-protein kinase, DM protein kinase, dystrophia myotonica protein kinase, myotonic dystrophy associated protein kinase, myotonin protein kinase A, thymopoietin homolog
Genomic Location:
Chr 19: 50964815-50977655
The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG t...
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 19

GO Molecular Function

cation binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | molecular function regulator | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | myosin phosphatase regulator activity | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | protein phosphatase regulator activity | transferase activity | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | heat shock protein binding | metal ion binding | heterocyclic compound binding | small molecule binding | phosphatase regulator activity

GO Biological Process

multicellular organismal movement | nucleus organization | regulation of muscle system process | regulation of dephosphorylation | intracellular signal transduction | regulation of localization | regulation of sodium ion transport | peptidyl-amino acid modification | regulation of skeletal muscle contraction by calcium ion signaling | regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction | regulation of phosphatase activity | cellular chemical homeostasis | membrane organization | cellular process | musculoskeletal movement | cellular homeostasis | endomembrane system organization | regulation of neurological system process | regulation of cell differentiation | regulation of myotube differentiation | regulation of cellular process | regulation of metabolic process | cellular component organization | calcium ion homeostasis | muscle contraction | response to stimulus | regulation of blood circulation | protein serine/threonine kinase activity | programmed cell death | nuclear envelope organization | protein modification process | regulation of synapse structure or activity | modulation of chemical synaptic transmission | macromolecule modification | molecular function regulator | metal ion homeostasis | regulation of membrane potential | apoptotic process | nitrogen compound metabolic process | regulation of signal transduction | modulation of excitatory postsynaptic potential | phosphorus metabolic process | regulation of muscle contraction | regulation of catalytic activity | cellular ion homeostasis | regulation of synapse organization | regulation of nitrogen compound metabolic process | second-messenger-mediated signaling | regulation of cellular protein metabolic process | phosphorylation | regulation of heart contraction | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | myosin phosphatase regulator activity | regulation of striated muscle contraction | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of synapse structural plasticity | regulation of protein metabolic process | cellular calcium ion homeostasis | homeostatic process | striated muscle contraction | calcium-mediated signaling | protein metabolic process | regulation of protein dephosphorylation | metabolic process | chemical homeostasis | protein kinase activity | organic substance metabolic process | cell death | protein phosphatase regulator activity | ion homeostasis | regulation of striated muscle cell differentiation | regulation of phosphate metabolic process | regulation of skeletal muscle contraction | regulation of cell communication | signaling | skeletal muscle contraction | cellular protein metabolic process | enzyme regulator activity | regulation of developmental process | regulation of ion transport | regulation of phosphoprotein phosphatase activity | kinase activity | organelle organization | regulation of muscle cell differentiation | regulation of cardiac conduction | peptidyl-serine phosphorylation | cellular protein modification process | regulation of transport | cellular metal ion homeostasis | cellular metabolic process | muscle cell apoptotic process | divalent inorganic cation homeostasis | regulation of cellular component organization | muscle system process | phosphatase regulator activity | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of organelle membrane | integral component of membrane | sarcoplasmic reticulum | intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cell | organelle outer membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | nuclear envelope | mitochondrion | nuclear outer membrane | intrinsic component of mitochondrial outer membrane | membrane-bounded organelle | sarcoplasmic reticulum membrane | nucleus | organelle | mitochondrial outer membrane | mitochondrial envelope | sarcoplasm | cell periphery | outer membrane | integral component of mitochondrial membrane | mitochondrial membrane | cytosol | intracellular | integral component of mitochondrial outer membrane | membrane