QuickView for DNA polymerase iota (gene)

Gene Symbol:

POLI Homo sapiens

Full name:

DNA polymerase iota

Synonyms:

RAD30B, RAD3OB, eta2, DNA polymerase iota, RAD30 homolog B, polymerase (DNA directed) iota, polymerase (DNA) iota, polymerase (DNA-directed), iota

Genomic Location:

Chr 18: 50049847-50078602

Description:

The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass t...

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The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGCGCANK_UNKNOWN

Cytogenetic Map:

18q21.2

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