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QuickView for DNAH11 (gene)


Gene Symbol:
DNAH11 Homo sapiens Homo sapiens
Full name:
dynein axonemal heavy chain 11
Synonyms:
CILD7, DNAHBL, DNAHC11, DNHBL, DPL11, dynein heavy chain 11, axonemal, axonemal beta dynein heavy chain 11, axonemal dynein heavy chain 11, ciliary dynein heavy chain 11, dynein, axonemal, heavy polypeptide 11, dynein, ciliary, heavy chain 11
Genomic Location:
Chr 7: 21549358-21907982
Description:
This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary C...
Orthologs:
Mus musculus Rattus norvegicus Canis lupus familiaris Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 7
7p15.3


Transcripts Names
NM_003777
NM_001277115
Protein Names
Q96DT5
Q9UJ82
H9NAJ7
Q96NT7
H9NAJ8



GO Molecular Function

dynein light intermediate chain binding | ribonucleotide binding | nucleotide binding | microtubule motor activity | hydrolase activity | carbohydrate derivative binding | dynein intermediate chain binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | motor activity | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ATP-dependent microtubule motor activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | dynein light chain binding | ATP-dependent microtubule motor activity, minus-end-directed | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

cell motility | regulation of localization | nervous system development | regulation of microtubule-based movement | cilium movement involved in cell motility | microtubule-based process | flagellated sperm motility | pattern specification process | cellular process | regulation of cilium movement | localization | heart morphogenesis | determination of left/right symmetry | sperm flagellum movement involved in flagellated sperm motility | regulation of cellular process | determination of heart left/right asymmetry | sperm motility | microtubule-based movement | locomotion | system development | multicellular organism development | epithelial cilium movement involved in determination of left/right asymmetry | learning or memory | determination of bilateral symmetry | nervous system process | animal organ morphogenesis | determination of left/right asymmetry in nervous system | regulation of cellular component movement | cognition | cardiac septum morphogenesis | cilium movement | cilium or flagellum-dependent cell motility | heart development | regulation of microtubule-based process | anatomical structure development | behavior | animal organ development | anatomical structure morphogenesis | cilium-dependent cell motility | regulation of cilium beat frequency | developmental process | cardiac septum development | cardiac chamber development | circulatory system development | epithelial cilium movement | multicellular organismal process

GO Cellular Component

supramolecular fiber | catalytic complex | microtubule associated complex | 9+0 motile cilium | dynein complex | proximal portion of axoneme | cell | microtubule | cytoplasm | intracellular organelle | 9+2 motile cilium | motile cilium | protein-containing complex | cell projection | plasma membrane bounded cell projection cytoplasm | cilium | microtubule cytoskeleton | cytoplasmic region | axoneme | organelle | ciliary plasm | cytoskeleton | intracellular | supramolecular complex