QuickView for DNASE1L3;jsessionid=8700D2B5A74F4BB15F1549BA47D3A3B9 (gene)

Gene Symbol:

DNASE1L3 Homo sapiens

Full name:

deoxyribonuclease 1 like 3

Synonyms:

DHP2, DNAS1L3, LSD, SLEB16, deoxyribonuclease gamma, DNase I homolog protein 2, DNase I homolog protein DHP2, DNase I-like 3, DNase gamma, LS-DNase, Liver and spleen DNase, deoxyribonuclease I-like 3, deoxyribonuclease I-like III

Genomic Location:

Chr 3: 58153394-58175438

Description:

This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

IRF1_01 ,  TATAAA_TATA_01 ,  STAT5A_03 ,  IRF_Q6 ,  CART1_01 ,  GATA1_05 ,  IRF2_01

Cytogenetic Map:

3p14.3

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