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QuickView for DNPH1;jsessionid=76135497AA9A1C2961CA7E3232018A32 (gene)


Gene Symbol:
DNPH1 Homo sapiens Homo sapiens
Full name:
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Synonyms:
C6orf108, RCL, dJ330M21.3, 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, c-Myc-responsive protein RCL, c-Myc-responsive protein Rcl, deoxyribonucleoside 5'-monophosphate N-glycosidase, putative c-Myc-responsive
Genomic Location:
Chr 6: 43301345-43305189
Description:
This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alt...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 6
6p21.1


Transcripts Names
NM_006443
NM_199184
Protein Names
O43598
A8MXA0
B2LUJ9



GO Molecular Function

hydrolase activity | hydrolase activity, hydrolyzing N-glycosyl compounds | catalytic activity | identical protein binding | hydrolase activity, acting on glycosyl bonds | protein binding | protein homodimerization activity | protein dimerization activity | deoxyribonucleoside 5'-monophosphate N-glycosidase activity

GO Biological Process

nucleoside phosphate catabolic process | cell differentiation | organophosphate catabolic process | cellular process | organic substance catabolic process | nucleotide metabolic process | tissue development | regulation of cellular process | positive regulation of cell growth | catabolic process | organic cyclic compound metabolic process | epithelium development | cellular aromatic compound metabolic process | purine nucleotide metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | phosphorus metabolic process | organophosphate metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | cell proliferation | biosynthetic process | aromatic compound biosynthetic process | nucleotide catabolic process | phosphate-containing compound metabolic process | aromatic compound catabolic process | regulation of growth | anatomical structure development | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | organonitrogen compound catabolic process | positive regulation of growth | developmental process | regulation of cell growth | epithelial cell differentiation | heterocycle metabolic process | cellular metabolic process | deoxyribonucleoside monophosphate catabolic process | regulation of cellular component organization | purine nucleotide catabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cytosol | intracellular